Dicentrin
Description Anti-cancer Activity- Product Name
- Dicentrin
- CAS No.
- 517-66-8
- Chemical Name
- Dicentrin
- Synonyms
- Nsc406035;dicentrine;DICENTRINE95%;(S)-dicentrine;o,N-Dimethyllitseferine;1,2-Methylenedioxy-9,10-dimethoxyaporphine;9,10-Dimethoxy-1,2-(methylenedioxy)aporphine;9,10-Dimethoxy-1,2-(methylenedioxy)-6aalpha-aporphine;1,2-(Methylenedioxy)-9,10-dimethoxy-6aalpha-aporphine;6A.alpha.-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)-
- CBNumber
- CB21178489
- Molecular Formula
- C20H21NO4
- Formula Weight
- 339.39
- MOL File
- 517-66-8.mol
Dicentrin Property
- Melting point:
- 177-178℃
- Boiling point:
- 481℃
- Density
- 1.266
- refractive index
- 1.6250 (estimate)
- Flash point:
- 143℃
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in DMSO
- pka
- 6.65±0.20(Predicted)
N-Bromosuccinimide Price
- Product number
- CS-0026026
- Product name
- Dicentrine
- Packaging
- 1mg
- Price
- $171
- Updated
- 2021/12/16
- Product number
- API0016457
- Product name
- DICENTRINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.69
- Updated
- 2021/12/16
- Product number
- CS-0026026
- Product name
- Dicentrine
- Packaging
- 5mg
- Price
- $514
- Updated
- 2021/12/16
- Product number
- 2300
- Product name
- Dicentrine
- Packaging
- 20mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- 2300
- Product name
- Dicentrine
- Packaging
- 100mg
- Price
- $1690
- Updated
- 2021/12/16
Dicentrin Chemical Properties,Usage,Production
Description
D-Dicentrine is an aporphinic alkaloid found in several plant species, mainly from family Lauraceae, including Lindera megaphylla. D-Dicentrine shows antinociceptive activity in a mouse model of pain. It probably acts via a TRPA1-dependent mechanism. D-Dicentrine is an alpha 1-adrenoceptor antagonist effective against human hyperplastic prostates.
Anti-cancer Activity
D-Dicentrine, a naturally occurring aporphine type isoquinoline alkaloid, isolated from the root of Lindera megaphylla Hemsl. (Lauraceae), was evaluated for its potential anti-cancer activity. Huang RL etc. found d-dicentrine significantly inhibited the growth of human hepatoma cell line HuH-7 by delaying its doubling time in tissue culture. An in vitro colony forming assay showed that d-dicentrine decreased the colony formation efficiency in both hepatoma cell lines, HuH-7 and MS-G2, used in our study.
Uses
d-Dicentrine is a natural aporphine alkaloid extracted from the root of L. megaphylla which displays antitumor effects through inhibition of topoisomerase II.
Definition
ChEBI: Dicentrine is an aporphine alkaloid.
Dicentrin Preparation Products And Raw materials
Raw materials
Preparation Products
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